中国实用内科杂志2024，Vol.44Issue(3)：177-181,5.DOI:10.19538/j.nk2024030101
体外生命支持下超保护性肺通气的实施
Ultra-lung-protective ventilation strategies under extracorporeal life support
摘要
Abstract
Lung-protective ventilation strategies are currently one of the standard treatments for patients with acute respiratory distress syndrome in an effort to provide adequate ventilatory requirements while minimizing ventilator-induced lung injury.With the in-depth understanding of ventilator-induced lung injury,more attention has been paid to the changes in the indicators of driving pressure,strain,transpulmonary pressure,mechanical power and in other indicators.Ultra-lung-protective ventilation can achieve lower tidal volume and airway pressure but better lung protection.Because application of ultra-lung-protective ventilation is often limited by respiratory acidosis,extracorporeal life support,represented by extracorporeal membrane oxygenation and extracorporeal carbon dioxide removal technology,is the key to ensuring the implementation of ultra-lung-protective ventilation.This article briefly describes the feasibility and effectiveness of ultra-lung-protective ventilation under extracorporeal life support and summarizes the main points of its implementation and existing problems,aiming to enhance our understanding of ultra-lung-protective ventilation and propose areas of future research.关键词
体外生命支持/体外膜肺氧合/体外二氧化碳清除/超保护性肺通气/呼吸机相关性肺损伤Key words
extracorporeal life support/extracorporeal membrane oxygenation/extracorporeal carbon dioxide removal/ultra-lung-protective ventilation/ventilator-induced lung injury分类
医药卫生引用本文复制引用
李敏,詹庆元..体外生命支持下超保护性肺通气的实施[J].中国实用内科杂志,2024,44(3):177-181,5.基金项目
重大呼吸系统疾病关键诊疗技术的临床研究和成果转化(2022-NHLHCRF-LX-01) （2022-NHLHCRF-LX-01）
