中国实用儿科杂志2024，Vol.39Issue(3)：183-192,10.DOI:10.19538/j.ek2024030604
儿童心肌炎病因学及发病机制进展
Progress in the etiology and pathogenesis of myocarditis in children
孙淑娜1
作者信息
- 1. 国家儿童医学中心 复旦大学附属儿科医院心血管中心,上海 201102
- 折叠
摘要
Abstract
Myocarditis is a common disease in children.Myocarditis is a disease characterized by localized or diffuse inflammatory lesions in the myocardial tissue,primarily manifested by myocardial cell necrosis and inflammatory cell infiltration in the interstitium.The etiology of myocarditis includes infectious and non-infectious causes.Viral infections have been proven to be the most common infectious cause,while autoimmune factors and drugs play a major role in non-infectious causes.The pathogenesis of myocarditis involves direct and secondary damage to myocardial cells,immunological mechanisms,abnormal gene signaling pathways,miRNA,genetic susceptibility,and other factors.ln recent years,there has been considerable attention given to myocarditis due to the global pandemic of the novel coronavirus and the widespread application its vaccine.This article elaborates on the current research status and progress of the etiology and pathogenesis of myocarditis.关键词
心肌炎/病因学/发病机制Key words
myocarditis/etiology/pathogenesis分类
医药卫生引用本文复制引用
孙淑娜..儿童心肌炎病因学及发病机制进展[J].中国实用儿科杂志,2024,39(3):183-192,10.
