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有氧运动干预慢性脑缺血学习记忆能力研究进展OACSTPCD

Research Progress on Aerobic Exercise Intervention for Learning and Memory Ability in Chronic Cerebral Ischemia

中文摘要英文摘要

积极的身体锻炼可以有效缓解慢性脑缺血(CCH)的病理进程,改善学习记忆能力.已有研究发现,有氧运动可通过改善海马组织上下通路活性,增强海马突触可塑性,提高神经保护作用和学习记忆能力.但是,有氧运动对慢性脑缺血的干预效果应充分考虑干预时机.对氧运动延缓慢性脑缺血病理进程、改善学习记忆可能的生物学机制进行综述.

Active physical exercise can effectively alleviate the pathological process of chronic cerebral ischemia(CCH)and improve learning and memory ability.This paper reviews the possible biological mechanisms of aerobic exercise to delay the pathological process of chronic cerebral ischemia and improve learning and memory.Previous studies have found that aerobic exercise can improve the neuroprotective effect,enhance the plasticity of hippocampal synapses,improve the activity of the upper and lower pathways of hippocampal tissue,and improve learning and memory ability.However,the intervention effect of aerobic exercise on chronic cerebral ischemia should be fully considered at the intervention time,and the intervention effect is also different.

王海军;邱良武;习杨彦彬;庞俊娣

连云港师范高等专科学校体育学院,江苏 连云港 222006昆明医科大学体育部,云南 昆明 650500昆明医科大学基础医学院,云南 昆明 650500

临床医学

慢性脑缺血有氧运动学习记忆能力运动干预神经保护

Chronic cerebral ischemiaAerobic exerciseLearning and memory abilityExercise interventionNeuroprotection

《昆明医科大学学报》 2024 (003)

Navβ2在脑老化认知功能减退病理进程中的作用及其调控机制研究

186-191 / 6

国家自然科学基金资助项目(81960210)

10.12259/j.issn.2095-610X.S20240328

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