协和医学杂志2024，Vol.15Issue(2)：251-257,7.DOI:10.12290/xhyxzz.2023-0574
超长效镇痛药物的研发与转化
Development and Translation of Super Long-acting Analgesics
摘要
Abstract
Pain management,listed as the fifth vital sign,has gained increasing attention from clini-cians.Conventional analgesics have limited duration,leading to intense monitor and frequent dosing during the early phase in order to prevent the progression of chronic pain.Thus,prolonging the duration of analgesics has become one focus of the pain research.Several strategies,such as adding adjuvants,producing derivatives,and applying extended-release carriers,make it possible for super long-acting analgesics to come into reality.This review briefly introduces the strategies and development of the super long-acting analgesics,including the suc-cessful translation and commercialization of the present products of super long-acting analgesics.It also summa-rizes the application and translation of extended-release drug carriers,providing invaluable reference for the fu-ture research on the field of super long-acting analgesics.关键词
超长效镇痛药/缓释药物载体/转化成果Key words
super long-acting analgesics/extended-release drug carriers/translational products分类
医药卫生引用本文复制引用
贺渝淼,李默晗,马超,黄宇光..超长效镇痛药物的研发与转化[J].协和医学杂志,2024,15(2):251-257,7.基金项目
中央高水平医院临床科研专项(2022-PUMCH-C-067) National High Level Hospital Clinical Research Funding(2022-PUMCH-C-067) （2022-PUMCH-C-067）
