遗尿儿童发生膀胱功能障碍的危险因素分析OA北大核心CSTPCD

Objective To explore the risk factors of bladder dysfunction in children with nocturnal enu-resis(NE).Methods From September 2020 to September 2022,343 NE children receiving urinary dynamic pressure-flow rate examination at Urinary Disorders Diagnosis and Treatment Center were selected as study sub-jects.According to the urodynamic results,they were assigned into two groups of bladder dysfunction(n=157)and non-dysfunction(n=186).Two groups were compared with regards to general profiles(gender,parental education,living environment,bedtime drinking water,history of enuresis,stool,daytime symptoms,weekly fre-quency of enuresis,bladder volume,urinary flow rate,residual urine & spina bifida),urinary routine,urological system ultrasonography,bococcygeal plain film and free urinary flow rate.Results There were 200 boys and 143 girls with a treatment age of(7.85±2.36)years.Male(OR=2.156,95％CI:1.085-4.285),daytime symptoms(OR=4.471,95％CI:2.229-8.967),lowered functional bladder volume(OR=20.651,95％CI:9.094-46.895),weekly frequency of enuresis＞4 times(OR=2.339,95％CI:1.131-4.838),reduced uri-nary flow rate(OR=3.196,95％CI:1.360-7.510)and occult spina bifida(OR=2.359,95％CI:1.160-4.794)were independent risk factors for bladder dysfunction in children.Conclusions Male,daytime symp-toms,occulted spina bifida,weekly frequency of enuresis＞4 times,lowered physiologic bladder volume and de-creased urinary flow rate are risk factors for bladder dysfunction in NE children.Routine urodynamic examina-tion is necessary to understand bladder function and provide rationales for standardized management.