婴幼儿脑室出血后脑积水的危险因素分析OA北大核心CSTPCD

Objective To explore the related risk factors of posthemorrhagic hydrocephalus(PHH)af-ter intraventricular hemorrhage(IVH)in infants.Methods From June 2013 to January 2022,retrospective a-nalysis was conducted for clinical data of 112 hospitalized children.Exploring the related factors of PHH by fol-lowing up on whether the patient has developed hydrocephalus after IVH.They were assigned into two groups of PHH(n=55)and resolved ventricular dilation(RVD,n=57).Univariate and multivariate Logistic regres-sions were utilized for examining the risk factors of hydrocephalus after IVH.Results And 55 cases(55/112,49％)developed PHH.58 cases(51.79％)received simple conservative symptomatic treatment;28 cases(25％)underwent lumbar puncture.Twenty-six patients(23.21％)received VPS treatment.The incidence of PHH was 49％(55/112).Among 112 children,5(4.46％)died from pulmonary insufficiency(n=2)and multiple organ failure(n=3).Among 107 survivors,there were epilepsy(n=3,2.80％),visual impairment(n=1,0.93％),hearing impairment(n=6,5.61％)had and cerebral palsy(n=5,4.67％)during follow-ups.The results of multivariate Logistic regression analysis showed;Gestational age at birth was 28 to 32 weeks(OR=19.078,95％CI:2.408-151.140,P=0.005)and prenatal steroids were not used(OR=20.642,95％CI:1.882-226.404,P=0.013)and high ventricular hemorrhage(OR=94.193,95％CI:16.583-535.043,P＜0.001)were independent risk factor for PHH.Conclusions Low gestational age,prenatal steroids were not used,and high ventricular hemorrhage are all associated with PHH in infants and young children with IVH.During the perioperative period,attention should be paid to the gestational age,weight,prenatal steroid use,and level of intraventricular hemorrhage in IVH patients,and timely intervention should be taken to prevent their de-velopment into PHH and improve their prognosis.