食品科学2024，Vol.45Issue(6)：261-270,10.DOI:10.7506/spkx1002-6630-20230613-105
食品中季铵盐类消毒剂检测方法建立及北京市市售食品及膳食样品中含量分析
Development of a Detection Method for Quaternary Ammonium Compounds in Foods and Its Application to Commercial Foods and Dietary Samples in Beijing
摘要
Abstract
An analytical method based on ultra-high performance liquid chromatography-tandem mass spectrometry was developed for the simultaneous detection of nine commonly used quaternary ammonium compounds(QACs)in various food matrices including vegetables,fruits,and aquatic products.The enrichment and purification of QACs were achieved using an improved quick,easy,cheap,effective,rugged and safe(QuEChERS)method,and the separation was performed on a BEH C18 column(100 mm×3.0 mm,1.7 μm)with gradient elution.QACs were detected using an electrospray ionization source in the positive ion mode.The limits of detection and quantification for the nine QACs in vegetables,fruits,and aquatic products were 0.2-5.0 and 1.0-10.0 μg/kg,respectively,and good linearity was observed for all analytes within their respective concentration ranges(R2>0.99).The recoveries for spiked samples were in the range of 65.24%-118.63%with relative standard deviations(RSDs)of 0.19%-6.77%.When the developed method was applied to commercial foods and dietary samples in Beijing,detection rates of 30.43%and 12%were obtained,respectively.The dietary risk of QAC residues was acceptable.关键词
季铵盐类消毒剂/QuEChERS/超高效液相色谱-串联质谱法/膳食摄入/食品安全Key words
quaternary ammonium compounds/quick,easy,cheap,effective,rugged and safe/ultra-high performance liquid chromatography-tandem mass spectrometry/dietary intake/food safety分类
轻工业引用本文复制引用
谢昀,周伟娥,许秀丽,张晶,张峰..食品中季铵盐类消毒剂检测方法建立及北京市市售食品及膳食样品中含量分析[J].食品科学,2024,45(6):261-270,10.基金项目
北京市科技计划课题项目(Z211100007021008) （Z211100007021008）
