国内中医药防治肺癌临床试验注册现况分析OACSTPCD

[Objective]To explore the registration characteristics and development trend of clinical trials related to the treatment of lung cancer with traditional Chinese medicine(TCM)registered in The Chinese Clinical Trial Registry(ChiCTR).[Methods]ChiCTR database was searched for clinical trials related to TCM treatment of lung cancer from its establishment to December 31,2021.Re-check and extract relevant data from retrieved clinical trials.Spss26.0 software was used for statistical analysis of the included data,and the characteristics of the clinical trial were summarized.[Results]A total of 94 clinical trials of TCM prevention and treatment of lung cancer were included,among which 85 were pre-registered.Clinical trial registration units are distributed in 17 provincial administrative regions and 40 clinical registration institutions.The top three regions for clinical trial registration were Beijing,Shanghai and Guangdong Province;The top three sources of funds were:24 items from local finance(25.53%),17 items from national finance(18.06%)and 14 items from self-raised funds(14.89%).The types of studies were mainly intervention studies,and only 17 studies were blind.[Conclusion]TCM prevention and treatment of lung cancer clinical trial registration number in China present a tendency of increasing overall,the researchers registered clinical consciousness increased significantly,but the poor design of experiment and normative,and the trial registration obvious uneven geographical distribution,advocate the researchers to strengthen clinical trial registration standardization,management are suggested to create more perfect registration system of audit,In order to further develop the advantages of TCM to prevent lung cancer in the future.