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孕期锌缺乏及对妊娠结局的影响

李运龙 李蕊 张玉萍 王瑞 刘燕萍

基础医学与临床2024,Vol.44Issue(4):422-427,6.
基础医学与临床2024,Vol.44Issue(4):422-427,6.DOI:10.16352/j.issn.1001-6325.2024.04.0422

孕期锌缺乏及对妊娠结局的影响

Zinc deficiency during pregnancy and its effect on pregnancy outcome

李运龙 1李蕊 1张玉萍 1王瑞 1刘燕萍1

作者信息

  • 1. 中国医学科学院 北京协和医学院 北京协和医院 临床营养科,北京 100730
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摘要

Abstract

Zinc deficiency during pregnancy is common and has been significantly associated with adverse pregnancy outcomes such as spontaneous preterm birth(PTB),recurrent abortion(RA),low birth weight(LBW),small-for-gestational-age infant(SGA),preeclampsia(PE),and gestational diabetes mellitus(GDM).Unfortunately,there is no specific biomarkers which are sensitive,easy-to-collect and detect available for the clini-cal evaluation of zinc nutritional status.However,recent studies have identified metallothionein and the ratio of oleic acid to dihydroxymethyl gamma-linolenic acid(LA/DGLA)as potentially candidates of biomarkers.This article focuses on summarizing and discussing the progress of domestic and international researches on zinc deficiency dur-ing pregnancy and adverse pregnancy outcomes,potential zinc biomarkers,and zinc deficiency treatments,aiming at providing ideas for perinatal nutritional guidance.

关键词

锌缺乏/锌生物标志物/妊娠结局

Key words

zinc deficiency/zinc biomarkers/pregnancy outcome

分类

医药卫生

引用本文复制引用

李运龙,李蕊,张玉萍,王瑞,刘燕萍..孕期锌缺乏及对妊娠结局的影响[J].基础医学与临床,2024,44(4):422-427,6.

基础医学与临床

OACSTPCD

1001-6325

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