1990-2019年中国睾丸癌疾病负担分析OA北大核心CSTPCD
Analysis of disease burden of testicular cancer in China from 1990 to 2019
目的 分析1990-2019年中国睾丸癌疾病负担及变化趋势.方法 基于2019年全球疾病负担数据库(GBD 2019),分析1990-2019年中国人群睾丸癌的发病、死亡、伤残调整寿命年(DALYs)、过早死亡损失寿命年(YLLs)、伤残损失寿命年(YLDs)及其变化趋势.通过计算年估计变化百分比(EAPC)评估年龄标准化率(ASR)的变化.按照年龄分组,分析睾丸癌疾病负担的年龄分布特点.结果 2019年中国睾丸癌发病例数为17.17×103例,死亡例数为1.21×103例,年龄标准化发病率为2.39/10万,年龄标准化死亡率为0.16/10万.与1990年相比,发病例数、死亡例数、年龄标准化发病率均明显增加或增高,与全球变化趋势一致,而增幅均高于全球水平,但中国和全球年龄标准化死亡率均呈现下降趋势.1990-2019年,中国睾丸癌的DALYs、YLLs、YLDs均明显上升,分别增加了29.66%、9.83%、720.91%.0～15岁和30～35岁是睾丸癌高发的两个年龄段,30～35岁是我国睾丸癌疾病负担最重的年龄段.结论 1990-2019年中国睾丸癌的疾病负担整体呈上升趋势.儿童和青壮年发病率较高、疾病负担较重,应作为睾丸癌的重点筛查及防治人群.
Objective To analyze the burden and changing trend of testicular cancer in China from 1990 to 2019.Methods Based on the 2019 Global Burden of Disease Database(GBD 2019),analyze the incidence,mortality,disability-adjusted life years(DALYs),years of life lost(YLLs),years lived with disability(YLDs)and their variation trend of testicular cancer in Chinese population from 1990 to 2019.Evaluating changes in age standardized rate(ASR)by calculating annual estimated percentage change(EAPC).According to the age grouping,analyze the age distribution characteristics of testicular cancer disease burden by age group.Results In 2019,the incident cases,deaths,age-standardized incidence rate,and age-standardized mortality rate of testicular cancer in China were 17.17×103,1.21×103,2.39/105,and 0.16/105,respectively.Compared to 1990,incident cases,deaths,and age-standardized incidence rate increased obviously in China,which was consistent with the global change trend,while the increase was higher than the global level.However,both Chinese and global age-standardized mortality rate showed a downward trend.From 1990 to 2019,DALYs,YLLs and YLDs of testicular cancer increased by 29.66%,9.83%and 720.91%respectively in China.The two age groups,0-15 years group and 30-35 years group,were with highest incidence of testicular cancer,while the highest disease burden of testicular cancer was 30-35 years.Conclusion From 1990 to 2019,the disease burden of testicular cancer in China showed an upward trend.Adolescents and young adults should be the priority population for screening and prevention due to their higher incidence and disease burden.
唐诗迪;訾豪;朱聪;王永博;曾宪涛
武汉大学中南医院泌尿外科,湖北武汉 430071||武汉大学中南医院循证与转化医学中心,湖北武汉 430071武汉大学中南医院循证与转化医学中心,湖北武汉 430071
临床医学
睾丸癌疾病负担发病率死亡率伤残调整寿命年
testicular cancerdisease burdenincidencemortalitydisability-adjusted life years
《解放军医学杂志》 2024 (003)
272-279 / 8
This work was supported by the National Development and Reform Commission and the National Health Commission Difficult Disease(Tumor Direction)Diagnosis and Treatment Capacity Enhancement Project(Development and Reform Office Social[2018]No.347) 国家发改委、国家卫健委疑难病症(肿瘤方向)诊治能力提升工程项目(发改办社会[2018]347号)
评论