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首页|期刊导航|四川医学|强脉冲光不同脉宽治疗面部激素依赖性皮炎后红斑毛细血管扩张疗效分析

强脉冲光不同脉宽治疗面部激素依赖性皮炎后红斑毛细血管扩张疗效分析OACSTPCD

Therapeutic Effect of Intense Pulsed Light with Different Pulsewidth on Patients with Facial Erythema and Telangi-ectasia After Steroid Dermatitis:a Retrospective Analysis

中文摘要英文摘要

目的 探讨采用强脉冲光的不同脉宽治疗面部激素依赖性皮炎后红斑毛细血管扩张患者的临床疗效及安全性.方法 收集我院皮肤性病科2016 年1 月至2021 年6 月收治的面部激素依赖性皮炎后红斑毛细血管扩张患者资料57 例,根据治疗方案进行分组,采用较长脉宽治疗的患者为A组(29 例),较短脉宽治疗的患者为B组(28 例).采用临床红斑评定量表(CEA)评价红斑改善情况,毛细血管扩张7 点评分标准(TGS)评价毛细血管扩张改善情况,统计分析两组患者治疗疗效及不良反应发生情况.结果 组间比较,两组CEA评分治疗后均降低,但A组CEA评分降低更明显,差异有统计学意义(P<0.05);两组TGS评分均增加,但两组间差异无统计学意义(P>0.05).治疗前后比较,随着治疗次数增加,两组治疗后与治疗前相比,CEA评分均明显降低,差异有统计学意义(P<0.05);TGS评分均明显增加,差异有统计学意义(P<0.05).结论 治疗面部激素依赖性皮炎后红斑毛细血管扩张患者,两种脉宽红斑和毛细血管扩张均得到较好改善;长脉宽较短脉宽红斑改善效果更好,安全性更高,增加治疗次数可提高疗效.

Objective To analyze clinical efficacy and safety of intense pulsed light(IPL)with different pulsewidths in the treatment of patients with facial erythema and telangiectasia after steroid-induced dermatitis.Methods Data of 57 patients with er-ythema and telangiectasia after steroid-induced dermatitis were collected and grouped according to the treatment protocol,including 29 cases treated with longer pulsewidth(group A)and 28 cases treated with shorter pulsewidth(group B).Clinical erythema assess-ment(CEA)and telangiectasia grading score(TGS)were used to evaluate the improvement of erythema and telangiectasia.Efficacy and adverse reactions were evaluated and recorded.Results After treatment,there were statistically significant difference in CEA scores between two groups(P<0.05),and no significant difference in TGS scores(P>0.05).With the increase of treatment times,the severity of erythema was decreased significantly(P<0.05),and clearance rate of telangiectasis was increased significantly in two groups(P<0.05).Conclusion The treatment of patients with facial erythema after steroid dermatitis with IPL,both erythema and telangiectasia improved significantly with two different pulse widths.Compared to the shorter pulsewidth,the longer pulsewidth has bet-ter improvement in erythema with higher safety and simple operation.If the number of treatments would be improved,the efficacy could be improved.

王英;李咏

四川大学华西医院皮肤性病科,四川 成都 610041

临床医学

强脉冲光红斑面部激素依赖性皮炎疗效脉冲宽度

intense pulse lighterythemasteroid dermatitisefficacypulsewidths

《四川医学》 2024 (003)

276-279 / 4

10.16252/j.cnki.issn1004-0501-2024.03.010

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