中国医疗美容2024，Vol.14Issue(3)：119-122,4.DOI:10.19593/j.issn.2095-0721.2024.03.029
瘢痕疙瘩表观遗传修饰的研究进展
Research Progress on Epigenetic Modification of Keloid
孔德祺 1金文玉 1金哲虎1
作者信息
- 1. 延边大学附属医院皮肤科,吉林 延吉,133000
- 折叠
摘要
Abstract
Keloid is a benign fibroproliferative skin disease that occurs after skin injury due to excessive connective tissue growth.It is characterized by an increase in volume beyond the original injury site,and is often accompanied by itching and pain.The exact mechanisms underlying the development of Keloids are still not fully understood,but epigenetic modifications,inflammatory responses,and mechanical forces have all been implicated.Among these factors,epigenetic modifications play a key role in the pathogenesis of Keloids by influencing fibroblast behavior and gene expression.This review aims to summarize the role of epigenetic modifications in Keloids,providing further insights into the understanding of its pathogenesis and potential innovative therapies.关键词
瘢痕疙瘩/表观遗传/DNA甲基化/组蛋白修饰/非编码RNAKey words
Keloid/Epigenetic/DNA Methylation/Histone Modification/Non-coding RNA引用本文复制引用
孔德祺,金文玉,金哲虎..瘢痕疙瘩表观遗传修饰的研究进展[J].中国医疗美容,2024,14(3):119-122,4.
