荷叶产地加工与饮片炮制一体化工艺研究OACSTPCD

Objective:To optimize the integrated technology of producing area processing and decoction pieces processing of lotus leaves(hereinafter refer to"integration").Methods:Nine different integrated processing technonogies were used to prepare the decoction pieces of lotus leaves.The content of alcohol-soluble extract was measured by hot-extraction method,and the contents of nuciferine,hyperin and isoquercitrin were measured by HPLC.At the same time,the products were compared with traditional lotus leaf decoction pieces prepared according to the method of the 2020 edition of Chinese Pharmacopoeia(partⅠ).Results:The best integrated technology was to bake fresh lotus leaves in a drying oven at 90℃until 70%dry(30%water content),remove the leaves and cut them into shreds,and then put them in a drying oven at 50℃.The integrated process had good stability and repeatability.Compared with the traditional processing technology,the alcohol-soluble extracts of lotus leaves decoction pieces prepared by the integrated process were similar,and the contents of nuciferine,hyperin and isoquercitrin were higher.Conclusion:The preferred integrated processing technology was simple,time-saving,and labor-saving,with high content of active ingredients.