ESBLs阳性肺炎克雷伯菌的研究进展OA

Klebsiella pneumoniae is a Gram-negative bacteria,belongs to Enterobacteriaceae,is facultally anaerobic,and often colonizes on the human upper respiratory tract and intestinal tract.It is an important opportunistic pathogen and one of the common pathogens of nosocomial infection.In recent years,due to the irrational use of antibiotics and other reasons,the drug resistance has been increasing year by year.The extended-spectrum β-lactamases(ESBLs),discovered since the 1980s,are one of the main causes of drug resistance of Klebsiella pneumoniae.In this paper,the drug resistance genes,typing and homology analysis ESBLs-producing Klebsiella pneumoniae are reviewed,so as to provide references for the prevention of ESBL-positive Klebsiella pneumoniae pneumonia and rational use of antibiotics in clinical treatment.