新癀片联合复方桐叶烧伤油治疗急性痛风性关节炎患者的疗效分析OA

Objective To observe the curative effect of Xinhuang tablets combined with Fufang Tongye Shaoshang You for patients with acute gouty arthritis.Methods A total of 96 patients with acute gouty arthritis treated at First Hospital,Medical College,Nanchang University from January 2022 to December 2022 were selected,and divided into group A,group B,and group C by the random number table method,with 32 cases in each group.There were 28 males and 4 females in group A;they were(53.37±16.53)years old;their acute disease course was(2.56±0.92)d.There were 30 males and 2 females in group B;they were(54.18±17.42)years old;their acute disease course was(2.53±0.89)d.There were 29 males and 3 females in group C;they were(53.61± 17.21)years old;their acute disease course was(2.61±0.93)d.The three groups were treated with conventional drugs;in addition,group A were treated with Xinhuang tablets,group B with Fufang Tongye Shaoshang You,and group C with Xinhuang tablets and Fufang Tongye Shaoshang You.All the three groups were observed 3 weeks.The general data(age,gender,body mass index,drinking,smoking,and acute disease course),scores of Visual Analogue Scale(VAS)and osteoarthritis index(WOMAC)before and 1,3,5,and 7 d after the treatment,and traditional Chinese medicine syndrome efficacies were compared between the 3 groups.t and x2 tests were applied.Results There were no statistical differences in the general data between the three groups(all P＞0.05).There were no statistical differences in the scores of VAS before and 1 d after the treatment between the three groups(both P＞0.05).There were statistical differences in the scores of VAS 3,5,and 7 d after the treatment between the three groups(all P＜0.05).The scores of VAS 3,5,and 7 d after the treatment in the group C[(4.84±1.30),(2.97±1.31),and(1.81±1.15)]were lower than those in group A[(5.63± 1.26),(4.34±1.33),and(2.97±1.28)]and group B[(6.38±1.21),(5.38±1.21),and(5.38±1.21)],with statistical differences(all P＜0.05).There were no statistical differences in the scores of WOMAC before and 1 d after the treatment between the three groups(both P＞0.05).There were statistical differences in the scores of WOMAC 3,5,and 7 d after the treatment between the three groups(all P＜0.05).The scores of WOMAC 3,5,and 7 d after the treatment in the group C[(113.50±28.78),(82.66± 31.82),and(50.19±34.90)]were lower than those in group A[(128.09±25.59),(110.31±28.29),and(87.84±33.19)]and group B[(154.19±20.59),(148.19±20.59),and(137.28±20.62)],with statistical differences(all P＜0.05).The total effective rate in group C was 96.9％(27/32),that in group A 78.1％(25/32),and that in group B 53.1％(17/32),with a statistical difference(x2=49.937,P＜0.001).Conclusion Xinhuang tablets combined with Fufang Tongye Shaoshang You for patients with acute gouty arthritis is effective,and can shorten their disease course,relieve their pain,and reduce the frequency of dressing replacement by clinical nurses.