单细胞RNA测序技术在肾病中的研究进展OA

Single-cell RNA sequencing(scRNA-seq)technology has brought many new discoveries to biomedical research,enabling high-resolution,high-throughput,and repeatable transcriptional analysis to identify new cell types and form cell maps.However,traditional sequencing methods can only reflect the overall level of gene expression of all cells in the samples and cannot reveal the heterogeneity of gene expression between individual cells.This article elaborates on the development history of scRNA-seq technology and outlines its potential application to reveal the mechanisms of kidney diseases,which is beneficial for diagnosis and treatment of kidney disease.