代谢组学在感染性疾病中的研究进展OA

Infectious diseases are one of the serious public health problems in the world,which are very harmful to human health.In recent years,metabolomics has been gradually applied to the research of infectious diseases to understand host-pathogen interactions at the small molecular level.By screening disease specific biomarkers through metabolomics based on nuclear magnetic resonance(NMR)or mass spectrometry(MS),new opportunities have been brought for disease prevention and exploration of etiology and pathogenesis.This review discusses the application of metabolomics in screening biomarkers,finding metabolites in infectious diseases such as virus,bacteria,and parasite infections,and the application of immunometabolomics,in order to provide new evidences for the diagnosis of infectious diseases.