早产儿初乳口腔免疫疗法的最佳证据总结OACSTPCD

Objective To retrieve and evaluate the best evidence for colostrum as oral immune therapy for premature infants at home and abroad,and to provide reference for clinical practice.Methods According to"6S"model,we systematically searched and collected the evidence regarding colostrum as oral immune therapy for premature infants.Two researchers evaluated the quality of the literature and extracted the data independently.Results Eleven pieces of literature were collected,including 3 guidelines,1 evidence summary,1 clinical decision,and 6 systematic reviews.Fifteen pieces of best evidence were obtained covering 4 aspects of suitable objects,intervention methods,management of colostrum and health education.Conclusion Colostrum as oral immune therapy could be delivered according to the best evidence.Clinical conditions and actual conditions of the preterm infants should be considered,so as to promote the maturity of the infants'immune system and reach the discharge standard as soon as possible.