食品科学2024,Vol.45Issue(9):330-338,9.DOI:10.7506/spkx1002-6630-20230316-160
肠道菌群介导的不同饮食模式与高尿酸血症相关性研究进展
Research Progress on the Correlation between Different Dietary Patterns and Hyperuricemia Mediated by Intestinal Flora
摘要
Abstract
Hyperuricemia(HUA)is a purine metabolism disorder caused by the imbalance between uric acid production and excretion,which,when severe,can lead to gout and renal function damage.At present,the prevalence of HUA/gout is increasing yearly in China and the HUA/gout patients are becoming younger and younger.Recent studies have shown that the intestinal flora of patients with HUA/gout is imbalanced when compared with that of healthy people,and different dietary patterns can affect the level of uric acid by adjusting the intestinal flora.This paper elaborates on the characteristics of the intestinal flora in patients with HUA/gout and the effect of the intestinal flora on uric acid metabolism,which will lay a theoretical foundation for the prevention,early diagnosis and auxiliary treatment of HUA/gout.This paper also summarizes recent progress in understanding the impact of different dietary patterns on uric acid levels in order to guide patients to effectively prevent and delay the occurrence of HUA/gout by adjusting their dietary patterns.关键词
高尿酸血症/痛风/肠道菌群/饮食模式Key words
hyperuricemia/gout/intestinal flora/dietary patterns分类
轻工纺织引用本文复制引用
卢涵,赵可新,薛玉玲,马新颖,王世杰..肠道菌群介导的不同饮食模式与高尿酸血症相关性研究进展[J].食品科学,2024,45(9):330-338,9.基金项目
河北省创新能力提升计划项目(22567685H) (22567685H)
石家庄后补助奖励专项资金项目(226790217H) (226790217H)
河北省重点研发计划项目(21322804D) (21322804D)