食品工业科技2024，Vol.45Issue(10)：412-422,11.DOI:10.13386/j.issn1002-0306.2023070123
壳寡糖的制备、纯化及应用研究进展
Research Progress on the Preparation,Purification and Application of Chitooligosaccharides
摘要
Abstract
Chitooligosaccharides(COS)is homo-or heterooligomers of N-acetylglucosamine and D-glucosamine obta-ined via degradation of chitin or chitosan.COS is useful for remarkably wide spectrum of applications in the pharm-aceutical,food,and agricultural industries due in part to their antimicrobial,antioxidant,antitumor,and immunomodulatory activities.Enzymatic,physical,and chemical methods for the preparation of COS has been reported.At present,the preparation of COS by any single method faces limitations,including difficulty in obtaining target products with specific degrees of polymerization and acetylation.Therefore,COS preparation protocols have shifted from single method strategies to explorations of cooperative catalytic systems.COS purity can also be improved by incorporating separation and purification techniques including ultrafiltration,activated carbon adsorption,and chromatography.In this paper,progress in COS preparation and purification methods and COS applications are reviewed,with the objective of providing a theoretical basis for improved production and expansion of applications for high quality COS.关键词
几丁质/壳聚糖/壳寡糖/制备/分离纯化/应用Key words
chitin/chitosan/chitooligosaccharides/preparation/separation and purification/application分类
轻工纺织引用本文复制引用
郭汉忠,李永莎,李永成,夏光华,张雪莹..壳寡糖的制备、纯化及应用研究进展[J].食品工业科技,2024,45(10):412-422,11.基金项目
海南省自然科学基金项目(320QN203) （320QN203）
海南省自然科学基金项目(322RC587) （322RC587）
海南大学科研启动基金项目(KYQD(ZR)20046). （KYQD(ZR）
