高等学校化学学报2024，Vol.45Issue(5)：10-27,18.DOI:10.7503/cjcu20230511
高效叠氮化方法研究进展
Research Progress in Efficient Azide Methods
摘要
Abstract
Organic azide compounds are a class of multifunctional compounds that are useful precursors for synthe-sizing a range of therapeutic drugs,bioactive compounds,functional materials,and high-energy compounds.They are widely used in click chemistry and Staudinger reactions.In the past few decades,a large number of synthesis strategies have been developed to prepare structurally diverse organic azides,but not all reactions can be carried out efficiently.As the concept of green chemistry deepens in people's hearts,traditional azide methods with low safety,universality,and efficiency are gradually being phased out,and the development of new and efficient azide methods is urgent.This review focuses on the efficient synthesis methods for preparing aliphatic azide compounds and azide polymers in recent years.A brief overview of the synthesis of aliphatic azide compounds is provided from the azide strategies of C—C multiple bonds and C—H bonds.The synthesis methods and potential novel synthesis strategies of azide polymers are also discussed,and the future development of azide chemistry is summarized and discussed.关键词
有机叠氮化合物/有机合成/脂肪族叠氮化物/高能化合物Key words
Organic azide compound/Organic synthesis/Aliphatic azide compound/High-energy compound分类
化学化工引用本文复制引用
龙磊,韦伟,罗运军,李霄羽..高效叠氮化方法研究进展[J].高等学校化学学报,2024,45(5):10-27,18.基金项目
国家自然科学基金(批准号:51973019,22175024)资助. Supported by the National Natural Science Foundation of China(Nos.51973019,22175024). （批准号:51973019,22175024）
