水产学报2024，Vol.48Issue(4)：22-32,11.DOI:10.11964/jfc.20230113866
鱼类白介素10的研究进展
Research progress on fish interleukin 10
摘要
Abstract
Interleukin 10(IL-10)is a multifunctional cytokine that participates in the immunity of the body.It is secreted by various immune cells such as monocytes and macrophages,and plays an important role in the develop-ment of various diseases such as tumor,infection and immune diseases.A variety of scleractinian fish IL-10 has been clonally expressed and has shown immunomodulatory effects,and there are a number of studies on the biolo-gical activity,mechanism of action,and regulatory mechanism of IL-10 in fish.To provide a reference for future studies and applications of fish IL-10,a literature review is conducted in terms of its genetic structure,transcrip-tional expression,origin and evolution,biological activities and functions,as well as fish IL-10 receptor and sig-naling pathway.关键词
白介素10(IL-10)/鱼类白介素10(fIL-10)/病毒白介素10(vIL-10)/生物学活性Key words
interleukin 10(IL-10)/fish interleukin 10(fIL-10)/viral interleukin 10(vIL-10)/biological activity分类
农业科技引用本文复制引用
黎秋男,李书含,周永恒,耿毅,黄小丽,陈德芳,欧阳萍..鱼类白介素10的研究进展[J].水产学报,2024,48(4):22-32,11.基金项目
国家自然科学基金(32102844) （32102844）
四川省国际科技创新合作项目(2020YFH0156) （2020YFH0156）
成都市科技局项目(2022YF0501021SN) National Natural Science Foundation of China(32102844) （2022YF0501021SN）
Sichuan International Science and Technology Innovation Cooperation Project(2020YFH0156) （2020YFH0156）
Chengdu Science and Technology Bureau Project(2022YF0501021SN) （2022YF0501021SN）
