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新生儿坏死性小肠结肠炎的外科手术治疗现状OA北大核心CSTPCD

Current status of surgical treatment for neonatal necrotizing enterocolitis

中文摘要英文摘要

坏死性小肠结肠炎(NEC)是新生儿时期常见的疾病,过去传统的认知认为只有在腹腔肠道穿孔的时候才需要进行外科手术干预治疗.但随着对于坏死性小肠结肠炎的病理病程变化的不断了解,人们开始寻找早期进行外科干预的方法.目前认为需要外科干预的相对指征主要参考临床表现、实验室检查和放射学检查的参数,一旦发现患儿临床情况恶化,则需要外科进行干预治疗.NEC的外科处理方式包括以下几种,腹腔放置腹腔引流管:单纯地放置腹腔引流可作为对于某些一般情况较差难以耐受手术的患儿或抢救中生命体征不平稳的最终选择;开腹探查术:在坏死肠管切除后进行肠道造口或吻合手术,特别是在局限病变的NEC患儿可以进行.对于一期肠吻合手术,在严重的、多灶性NEC,由于病变肠管较多,国外多采用空肠造瘘的高位置空肠造口术或采用对于残余肠管的"夹闭并放回腹腔"技术以提高患儿生存率;NEC情况下腹腔镜的使用:目前国内外尚报道不多,该技术对于急症的患儿存在加重腹腔内CO2压力,增加麻醉风险和患儿内环境恶化的不利因素,目前尚无更多的数据支持广泛地使用该技术于NEC的患儿.

Necrotizing enterocolitis(NEC)is a common disease in the newborn period.In the past,the traditional cognition believed that surgical intervention was only needed when abdominal and intestinal perforation occured.However,with the continuous understanding of the pathological course of necrotizing enterocolitis,people began to look for early surgical intervention methods.At present,the relative indications for requiring surgical intervention are mainly based on the parameters of clinical manifestations,laboratory examination and radiological examination.Once the clinical condition of the child is found to deteriorate,surgical intervention is required.The surgical management of NEC includes the following types.The abdominal placement of abdominal drainage tube:the simple placement of abdominal drainage can be used as the final choice for some children with poor general conditions who can't tolerate surgery or with unstable vital signs in the rescue.Open exploration:intestinal stomy or anastomosis can be done after necrotic bowel resection,especially in children with NEC with localized lesions,who can have intestinal anastomosis.In severe,multifocal NEC,due to the more diseased bowel tubes,jejunostomy with high position or"clip and drop back"technology is used to improve the survival rate of children;Use of laparoscopy in NEC:few cases are reported at home and abroad.This technique exacerbates intraabdominal CO2 pressure in children with emergencies,increases the risk of anesthesia and internal environmental deterioration in the children.There are no additional data to support the widespread use of this technology in children with NEC.

杜京斌;黄金狮

首都医科大学附属北京儿童医院小儿外科,北京 100045

临床医学

坏死性小肠结肠炎新生儿外科干预

necrotizing enterocolitisneonatesurgical intervention

《中国实用儿科杂志》 2024 (005)

334-338 / 5

10.19538/j.ek2024050604

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