中国耳鼻咽喉头颈外科2024，Vol.31Issue(4)：236-241,6.DOI:10.16066/j.1672-7002.2024.04.007
累及鼻腔鼻窦的Rosai-Dorfman病临床特征分析
Analysis of the clinical charateristics of Rosai-Dorfman disease in nasal cavity and paranasal sinuses
摘要
Abstract
OBJECTIVE To explore the clinical characteristic manifestation of Rosai-Dorfman disease(RDD)involving the nasal cavity and paranasal sinuses.METHODS The clinical data of 16 patients with RDD involving the nasal cavity and paranasal sinuses who received treatment in Department of Rhinology of Beijing Tongren Hospital Affiliated to Capital Medical University from December 2016 to December 2023,were retrospective analyzed.RESULTS The male to female ratio was 1:3,with an average age of 47.4 years and an average disease duration of 22.34 months.There were 14,3,5,6 and 1 patients who complained of nasal congestion,dry nose,decreased sense of smell,head and face pain,and bulging/diplopia,respectively.There were 9 patients who had external nasal swelling.There were 14 RDD patients who were involved at least the nasal septum,12 patients who were simply affected in the nasal cavity,and 3 cases who involved the paranasal sinuses.There was 1 case belonged to a mixed type of RDD.There were 8 of 10 cases who were misdiagnosed or missed due to intraoperative rapid freezing.Endoscopic examination showed bilateral bulging in 9 patients'nasal septum,and nodular or granular new growth on 7 patients'nasal floor and inferior turbinate surface.Sinus CT found 9 patients'the nasal septum area showed a circular uniform soft tissue shadow or symmetrical soft tissue thickening shadow,5 patients'nasal floor and inferior turbinate showed obvious soft tissue thickening shadow.CONCLUSION RDD involving the nasal cavity and paranasal sinuses has certain typical features in external nasal manifestations,endoscopic and imaging examinations.Comprehensive judgment can help improve the feasibility of clinical diagnosis of RDD.关键词
鼻腔/鼻窦疾病/诊断,计算机辅助/Rosai-Dorfman病/临床特征/影像学Key words
Nasal Cavity/Paranasal Sinus Diseases/Diagnosis,Computer-Assisted/Rosai-Dorfman disease/clinical features/radiology引用本文复制引用
郑铭,司马宇彤,庄梦岩,王向东,张罗..累及鼻腔鼻窦的Rosai-Dorfman病临床特征分析[J].中国耳鼻咽喉头颈外科,2024,31(4):236-241,6.基金项目
国家重点研发计划(2022YFC2504100) （2022YFC2504100）
教育部长江学者创新团队(IRT13082) （IRT13082）
中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-022) （2019-I2M-5-022）
首都卫生发展科研专项重点攻关项目(2022-1-1091) （2022-1-1091）
国家自然科学基金(81970852、82171110) （81970852、82171110）
北京市自然科学基金(7222024) （7222024）
首都医科大学科研培育基金(2020-1210020214) （2020-1210020214）
