食品与发酵工业2024，Vol.50Issue(9)：307-313,329,8.DOI:10.13995/j.cnki.11-1802/ts.036489
基于肠道菌群调节的膳食纤维影响抑郁的研究
Effects of dietary fiber on depression based on the regulation of intestinal flora
摘要
Abstract
Due to the increasing pressure of work and life,the prevalence of depression is also rising year by year.As the invisible or-gan of human body,gut microbiota plays an important role in human life and health,and has become a research hotspot in the field of life science in recent years.With the deepening of research on gut microbiota,there is increasing evidence that gut microbiota can improve de-pression symptoms through the gut-brain axis.Dietary fiber,as a unique plant polysaccharide,can effectively regulate intestinal flora dis-turbances.The key role of dietary fiber in coordinating host-microbiome crosstalk has been proven.This paper reviews the evidence of the effects of dietary fiber on intestinal flora and depression,focusing on the mechanism of dietary fiber intervention in intestinal flora to im-prove depression,in order to provide new ideas and references for the prevention and adjuvant treatment of depression.关键词
膳食纤维/抑郁症/肠道菌群/短链脂肪酸/色氨酸Key words
dietary fiber/depression/intestinal flora/short chain fatty acid/tryptophan引用本文复制引用
白丽,乔艺,程晓宇,许嘉乾,余婕,尹季忠,黄涛,崔晟轩,刘辉,解瑞宁..基于肠道菌群调节的膳食纤维影响抑郁的研究[J].食品与发酵工业,2024,50(9):307-313,329,8.基金项目
国家自然科学基金青年基金项目(31600947) （31600947）
山东省自然科学基金面上项目(ZR2022MC039) （ZR2022MC039）
济宁医学院贺林院士新医学临床转化工作站项目(JYHL2021MS03) （JYHL2021MS03）
