食品与发酵工业2024，Vol.50Issue(9)：321-329,9.DOI:10.13995/j.cnki.11-1802/ts.035889
乳铁蛋白的重组表达系统及法规管理现状概述
Overview of recombinant expression systems and regulation status of lactoferrin
摘要
Abstract
Lactoferrin is an iron-binding glycoprotein widely found in mammal milk and mucosal secretions.Lactoferrin has broad-spectrum antibacterial,antiviral,immunomodulatory,and other physiological functions,and is used in various fields,such as infant for-mula milk powder,nutritional supplements,and cosmetics.In recent years,with the continuous development of genetic engineering tech-nology,lactoferrin from different species has been successfully expressed in common prokaryotic expression systems,eukaryotic expression systems,and transgenic mammals.Meanwhile,the expression of recombinant products and their structural similarity to natural lactoferrin have been increasing.This report reviewed the biological activity,recombinant expression systems,and current regulations of lactoferrin.Furthermore,the challenges and future development directions of recombinant lactoferrin were discussed.关键词
乳铁蛋白/生理活性/重组表达系统/法规/应用Key words
lactoferrin/physiological activity/recombinant expression system/regulation/application引用本文复制引用
吴晓文,张长太,李佳佳,凡孝菊,周景文..乳铁蛋白的重组表达系统及法规管理现状概述[J].食品与发酵工业,2024,50(9):321-329,9.基金项目
江苏省自然科学基金前沿引领技术基础研究专项(BK20202002) （BK20202002）
