中医药治疗儿童咳嗽变异性哮喘用药规律研究OACSTPCD

[Objective]Through data mining of ancient and modern medical record cloud platform,the medication law of Traditional Chinese medicine(TCM)for children cough variant asthma(CVA)was analyzed.[Methods]A comprehensive search was conducted for the literatures related to TCM treatment of children CVA in China Biomedical Literature Service System(SinoMed),China Journal Full-text Database(CNKI),VIP Chinese Scientific and Technological Journal Full-text Database(VIP)and WanFang Data Knowledge Service Platform(WanFang)from the self-built database until December 31,2021.Relevant TCM prescriptions were imported into Excel 2018 and standardized database was established.Finally,frequency analysis,TCM attribute analysis,association rule analysis,cluster analysis and other data mining were conducted through the ancient and modern medical case cloud platform software to analyze the medication rule of TCM in the treatment of children CVA.[Results]A total of 190 literatures were included in this study,including 214 prescriptions,totaling 203 TCMs.The top 10 TCMs in frequency from high to low were bitter almond,glycyrrhiza,prepared ephedra,pinellia ternata,dipterocarpus cicadae,perilla fruit,scutellaria baicalensis,platycodon platycodon and schisandrae.The medicinal properties of the herbs were mainly warm,the medicinal taste was mainly acanthic,and the main channels were lung,spleen,stomach and liver.26 drug compatibility rules were obtained by association rule analysis,and 4 core combinations were obtained by evolution.[Conclusion]In the treatment of children CVA with modern Chinese medicine,xinwen products are mostly used.Starting from the three organs of lung,spleen and stomach,the methods of promoting lung,eliminating phlegm,lowering qi and relieving asthma are adopted.