天津中医药大学学报2024，Vol.43Issue(4)：348-355,8.DOI:10.11656/j.issn.1673-9043.2024.04.10
三七总皂苷及其制剂治疗糖尿病视网膜病变的研究进展
Research progress of Panax notoginseng saponins and its preparation in the treatment of diabetic retinopathy
摘要
Abstract
Diabetic retinopathy(DR)is a common complication of diabetes and the main cause of blindness in diabetics,which seriously affects the quality of life of diabetics.At present,the main clinical treatment methods of DR include surgical treatment,laser treatment and drug treatment.Among them,drug therapy can intervene in multiple aspects of disease development and reduce complications related to laser treatment and surgical treatment.However,due to the particularity of the eye structure,the bioavailability of drugs is low,and there is an urgent need to seek and develop drugs with good efficacy and low toxic side effects and suitable dosage forms.Traditional Chinese medicine has the advantages of long history,wide origin,multi-target synergy,etc.,and has unique advantages in the treatment of DR.Panax notoginseng saponins are the main active ingredient group extracted from Panax notoginseng,which has been confirmed to have the effect of treating DR.In this paper,the mechanism of Panax notoginseng saponins in the treatment of DR and the dosage forms of Panax notoginseng in the clinical application was analyzed and summarized,which broadens the horizon of the development of pharmaceutical dosage forms of Panax notoginseng saponins.关键词
糖尿病视网膜病变/中药/三七总皂苷/剂型Key words
diabetic retinopathy/traditional Chinese medicine/Panax notoginseng saponins/dosage form分类
医药卫生引用本文复制引用
于长祥,钟雨虹,邢斌,贾欣陶,张瀛,张青青,刘志东..三七总皂苷及其制剂治疗糖尿病视网膜病变的研究进展[J].天津中医药大学学报,2024,43(4):348-355,8.基金项目
中央引导地方科技发展专项项目(21ZYJDJC00020) （21ZYJDJC00020）
现代中医药海河实验室科技项目(22HHZYSS00005) （22HHZYSS00005）
天津市研究生科研创新项目(2021YJSS185). （2021YJSS185）
