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Comparing role of ATP between acute pain in neuromyelitis optica spectrum disorder and peripheral neuropathic painOA

中文摘要

In this article, we present our previous research, which highlighted adenosine triphosphate(ATP) as the cause of neuropathic pain during the acute phase of neuromyelitis optica spectrum disorder(NMOSD). In NMOSD pathology, damageassociated molecular patterns(DAMPs), including ATP, are released from damaged astrocytes, triggering the activation of innate immune cells. ATP is a central mediator of acute pain in NMOSD.

Teruyuki Ishikura;Tatsusada Okuno;

Department of Molecular Neuroscience,Graduate School of Medicine,Osaka University,Osaka,JapanDepartment of Neurology,Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan

中医学

painacutepathology

《Neural Regeneration Research》 2025 (001)

P.184-185 / 2

10.4103/NRR.NRR-D-23-01637

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