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首页|期刊导航|Neural Regeneration Research|Roles of N-cadherin in cerebral cortical development:cooperation with membrane trafficking and actin cytoskeletal regulation

Roles of N-cadherin in cerebral cortical development:cooperation with membrane trafficking and actin cytoskeletal regulationOA

中文摘要

Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junctions),and macula adhaerens(desmosomes).Although these adhesion complexes are basically observed only in epithelial cells,cadherins,which are the major cell adhesion molecules of adherens junctions,are expressed in both epithelial and non-epithelial tissues,including neural tissues(Kawauchi,2012).The cadherin superfamily consists of more than 100 members,but classic cadherins.

Shiho Ito;Takeshi Kawauchi;

Department of Adaptive and Maladaptive Responses in Health and Disease,Graduate School of Medicine,Kyoto University,Kyoto,JapanDepartment of Adaptive and Maladaptive Responses in Health and Disease,Graduate School of Medicine,Kyoto University,Kyoto,Japan Department of Physiology,Keio University School of Medicine,Tokyo,Japan

临床医学

cerebralskeletalcooperation

《Neural Regeneration Research》 2025 (001)

P.188-190 / 3

funded by JSPS KAKENHI Grant Numbers JP26290015 and JP21H02655(to TK)from Ministry of Education,Culture,Sports,Science,and Technology of Japan(MEXT)。

10.4103/NRR.NRR-D-23-02069

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