|国家科技期刊平台
首页|期刊导航|临床误诊误治|误诊为急性胃炎及肠梗阻的高脂血症性急性胰腺炎临床分析

误诊为急性胃炎及肠梗阻的高脂血症性急性胰腺炎临床分析OACSTPCD

Clinical Analysis of Hyperlipidemic Acute Pancreatitis Misdiagnosed as Acute Gastroenteritis and Intestinal Obstruction

中文摘要英文摘要

目的 总结高脂血症性急性胰腺炎(HAP)误诊为急性胃炎及肠梗阻的原因及防范措施.方法 回顾分析2022 年7 月—2023 年7 月收治曾误诊的HAP 2 例的临床资料.结果 本组1 例表现为恶心、呕吐、腹胀,外院初诊为急诊胃炎,予对症治疗无缓解且出现尿量减少,入我院后查血示肾功能不全及高钾血症,完善血淀粉酶、脂肪酶、血脂及全腹CT检查诊断为HAP,予相应治疗20d后恢复良好出院.1 例因上腹痛伴恶心、呕吐诊断为急性胃肠炎,入我院后腹部X线透视见液气平,查血尿淀粉酶不高,拟诊肠梗阻,行对症治疗腹痛无好转,遂剖腹探查见胰腺水肿并坏死,腹水淀粉酶升高,结合血三酰甘油、胆固醇升高,诊断HAP.予相应治疗 15d后恢复良好出院.结论 HAP患者腹痛症状无特异性,血尿淀粉酶可出现假阴性结果,若接诊医生对该病认知不足,易误诊.加强临床医生对HAP认识,仔细询问病史,开拓诊断思路,及早行血脂、血尿淀粉酶和腹部B超、CT等检查,可减少或避免HAP早期误诊.

Objective To summarize the causes and preventive measures of hyperlipidemic acute pancreatitis(HAP)misdiagnosed as acute gastritis and intestinal obstruction.Methods The clinical data of 2 misdiagnosed HAP patients admit-ted from July 2022 to July 2023 were retrospectively analyzed.Results One patient in this group presented with nausea,vomiting and abdominal distension,and was initially diagnosed as emergency gastritis in another hospital,which was not re-lieved by symptomatic treatment and led to decreased urinary volume.After admission to our hospital,blood examination indi-cated renal insufficiency and hyperkalemia,and HAP was diagnosed by examination of blood amylase,lipase and lipid and whole abdominal CT examination.After 20 days of corresponding treatment,the patient recovered well and was discharged.Another patient was diagnosed as acute gastroenteritis due to upper abdominal pain accompanied by nausea and vomiting.After admission to our hospital,the abdominal X-ray examination showed air fluid level and no increase in the blood and urine amyl-ase,which was suspected to be intestinal obstruction.Symptomatic treatment was performed,and the abdominal pain did not improve.Then the laparotomy revealed pancreatic edema and necrosis,elevated ascites amylase,combined with elevated blood triglyceride and cholesterol,and HAP was diagnosed.At 15 days after treatment,the patient recovered well and was discharged.Conclusion The symptoms of abdominal pain in HAP patients are non-specific,and the results of hematuric am-ylase may be false negative.Insufficient understanding of this disease for the clinician may lead to misdiagnosis.It is necessa-ry to strengthen the clinician's understanding of HAP,carefully inquire about the history,develop the diagnosis idea,and per-form blood lipids,blood and urine amylase,abdominal B-ultrasound,CT and other examinations to reduce or avoid the early misdiagnosis of HAP.

阚丽娜;刘微

066000 河北 秦皇岛,北京大学第三医院秦皇岛医院消化科066000 河北 秦皇岛,北京大学第三医院秦皇岛医院风湿免疫科

临床医学

胰腺炎高脂血症误诊胃炎胃肠炎肠梗阻淀粉酶脂肪酶

PancreatitisHyperlipidemiasMisdiagnosisGastritisGastroenteritisIntestinal obstructionDia-staseLipase

《临床误诊误治》 2024 (006)

1-4 / 4

秦皇岛市科学技术研究与发展计划项目(202201B018)

10.3969/j.issn.1002-3429.2024.06.001

评论