中国食品添加剂2024，Vol.35Issue(5)：324-332,9.DOI:10.19804/j.issn1006-2513.2024.5.037
适配体生物传感器检测细菌毒素的研究进展
Research progress on aptamer biosensors for detection of bacterial toxin
摘要
Abstract
Bacterial toxins are secondary metabolites produced by bacteria and are one of the major threats to human health.The contamination of bacterial toxins in food has become one of the main food safety problems that people pay urgent attention to.Therefore,it is of great significance to develop a simple,rapid and sensitive method for detecting bacterial toxins in food.Nucleic acid aptamers are single strand oligonucleotide sequences screened in vitro,which can specifically identify the targets.It has the advantages of easy synthesis,easy labeling,easy modification,high sensitivity,high specificity and low molecular weight,etc.,and is widely used in biosensors.This paper briefly introduced the classification and harm of bacterial toxins,and focused on the latest progress and applications of aptamer biosensors based on optical and electrochemical technologies in the detection and quantification of bacterial toxins,in order to provide research basis for the detection of bacterial toxins.关键词
适配体/生物传感器/细菌毒素/检测/进展Key words
aptamer/biosensor/bacterial toxin/detection/progress分类
轻工业引用本文复制引用
崔丽伟,常惟丹,陈威风,邹建,姬向波..适配体生物传感器检测细菌毒素的研究进展[J].中国食品添加剂,2024,35(5):324-332,9.基金项目
河南省科技攻关项目(232102320281,232102320285) （232102320281,232102320285）
河南省高等学校重点科研项目计划(23A550021) （23A550021）
