北京中医药大学学报2024，Vol.47Issue(5)：598-602,5.DOI:10.3969/j.issn.1006-2157.2024.05.002
从获得性脑淀粉样血管病病机探讨"毒损脑络"的新内涵
Discussing the new implications of"toxins damaging brain collaterals"from the pathogenesis of acquired cerebral amyloid angiopathy
摘要
Abstract
Acquired cerebral amyloid angiopathy,as a cerebrovascular disease discovered in recent years,mainly spreads through iatrogenic factors.This paper focuses on acquired cerebral amyloid angiopathy and delves into the new applications and profound implications of the"toxins damaging brain collaterals"theory proposed by academician WANG Yongyan in stroke research.Starting from the perspective of"toxins damaging brain collaterals",it comprehensively analyzes the causes and pathological mechanisms of acquired cerebral amyloid angiopathy,emphasizing the importance of external toxins,latent toxins,and turbid toxins in understanding the pathogenesis of the disease.It reveals that"toxins damaging brain collaterals"is the core mechanism of acquired cerebral amyloid angiopathy.On this basis,it proposes a new connotation of"toxins damaging brain collaterals":first,"toxin"includes both internal and external toxins;second,the organic integration of"external wind theory"and"toxins damaging brain collaterals"guides the improvement of theoretical research,clinical treatment,and prevention strategies for stroke,and promotes a deeper understanding of the disease.This approach to understanding acquired cerebral amyloid angiopathy from the perspective of"toxins damaging brain collaterals"not only demonstrates the effective integration of traditional Chinese medicine theory and modern biomedical science,but also provides insights and references for the clinical diagnosis and treatment of the disease.关键词
毒损脑络/外毒/获得性脑淀粉样血管病/医源性脑淀粉样血管病/脑淀粉样血管病Key words
toxins damaging brain collaterals/external toxins/acquired cerebral amyloid angiopathy/iatrogenic cerebral amyloid angiopathy/cerebral amyloid angiopathy分类
医药卫生引用本文复制引用
张帆,刘佳霖,姜俊辰,张元馨,陈俊龙,刘金民..从获得性脑淀粉样血管病病机探讨"毒损脑络"的新内涵[J].北京中医药大学学报,2024,47(5):598-602,5.基金项目
国家自然科学基金项目(No.81774277) （No.81774277）
北京中医药大学2020年度基本科研业务费项目(No.2020-tslXK-01) （No.2020-tslXK-01）
北京中医药大学2020年度重点攻关项目(No.2020-JYB-ZDGG-131) National Natural Science Foundation of China(No.81774277) （No.2020-JYB-ZDGG-131）
