中医药特色化干预对不同证候阈下抑郁患者的疗效及安全性比较OACSTPCD

Objective To explore the efficacy of TCM intervention on subthreshold depression patients with different syndromes by employing the method of Yule Drink(Depression Removing Drink)+group psychotherapy(situational salon)+wood-jue-scale music therapy.Methods 76 patients with subthreshold depression were randomly divided into an experimental group(n=56)and a control group(n=20).The experimental group received intervention through group psychotherapy(situational salon)+Yule Drink+wood-jue-scale music therapy,while the control group underwent group psychotherapy(situational salon)only.The duration of treatment was 12 weeks,and CES-D,HAMD-17,Traditional Chinese Medicine Syndrome Scale,and safety indicators are measured before and after the intervention.Results After 12 weeks of intervention,both groups showed a significant reduction in CES-D and HAMD-17 scale scores compared to pre-intervention(P<0.05).Patients with liver depression and spleen deficiency syndrome exhibited a statistically significant reduction in HAMD-17 scale scores after treatment(P<0.05).Conclusions Yule Drink+group psychotherapy+wood-jue-scale music therapy can effectively improve the subthreshold depression of patients with liver depression and spleen deficiency syndrome,while alleviating their physical symptoms.