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L-茶氨酸口溶膜的制备及其成膜条件的优化

曲超楠 李木子 李林珏 赵晓娜 刘永夏 戴培强 刘建柱

动物医学进展2024,Vol.45Issue(7):60-63,4.
动物医学进展2024,Vol.45Issue(7):60-63,4.

L-茶氨酸口溶膜的制备及其成膜条件的优化

Preparation of L-theanine Orodispersible Film and Optimization of Its Film-forming Conditions

曲超楠 1李木子 1李林珏 1赵晓娜 1刘永夏 1戴培强 2刘建柱1

作者信息

  • 1. 山东农业大学动物科技学院,山东泰安 271000
  • 2. 山东戴尔塔生物工程有限公司,山东泰安 271000
  • 折叠

摘要

Abstract

Theanine is a characteristic non-proteinogenic amino acid which has anti-stress,stabilizing emotions,sleep improvement,immune regulation,anti-inflammatory and other pharmacological actions in tea plants.This experi-ment aims to fabricate the L-theanine orodispersible film and evaluate the quality.The content of L-theanine,HPMC and glycerol,oven temperature,drying time were explored by single factor test and orthogonal test.The composition ratio and preparation conditions of the film forming prescription were optimized.The experiment re-sults showed that the optimum ratio of L-theanine orodispersible film was L-theanine 0.5 g,HPMC 1.8 g,glycerol 0.5 mL,titanium dioxide 0.02 g mixed with 12 mL water,and the optimum drying condition was drying at 60℃ for 100 min.The physical properties,L-theanine content and weight variation meet the requirements,which was expec-ted to provide data support for pet clinical medication.

关键词

茶氨酸/口溶膜剂/流延法/制备工艺

Key words

L-theanine/orodispersible film(ODF)/agent casting method/preparation process

分类

农业科技

引用本文复制引用

曲超楠,李木子,李林珏,赵晓娜,刘永夏,戴培强,刘建柱..L-茶氨酸口溶膜的制备及其成膜条件的优化[J].动物医学进展,2024,45(7):60-63,4.

动物医学进展

OA北大核心CSTPCD

1007-5038

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