基于有氧糖酵解探讨天然产物干预肝癌的研究进展
The research progress of natural products in the intervention of liver cancer based on aerobic glycolysis
摘要
Abstract
Liver cancer is a common malignant tumor with high morbidity and mortality.In the process of rapid proliferation,the energy demand of liver cancer cells increases,leading to metabolic reprogramming of liver cancer cells.Among them,aerobic glycolysis is often referred to as the"Warburg effect",which can promote rapid proliferation,invasion and metastasis of liver can-cer.Aerobic glycolysis can not only provide energy for liver cancer cells,but also provide raw materials for the synthesis of various biological macromolecules in liver cancer cells,which will promote the progress of liver cancer clinically.Therefore,the use of tu-mor aerobic glycolysis can be used as a potential target for cancer treatment.Natural products are important sources for the develop-ment of anti-tumor drugs.In recent years,searching for natural products to target aerobic glycolysis and intervene in the progress of liver cancer has become a research hotspot.关键词
有氧糖酵解/天然产物/肝癌/研究进展Key words
Aerobic glycolysis/Natural products/Liver cancer/Research progress分类
医药卫生引用本文复制引用
王帆,赵戈蕾,张晓青,李东东,刘培民..基于有氧糖酵解探讨天然产物干预肝癌的研究进展[J].海南医学院学报,2024,30(10):784-789,6.基金项目
This study was supported by National Natural Science Foundation of China(82204981) （82204981）
the National Clinical Research Base of Traditional Chinese Medicine(2021JDZX2002) （2021JDZX2002）
Research on Public Information Platform of Esophageal Traditional Chinese Medicine Literature Database(STG-ZYY06202146) （STG-ZYY06202146）
Doctoral Research Fund of Henan University of Traditional Chinese Medicine(2022BSJJ08) （2022BSJJ08）
Doctoral Research Fund of Henan University of Traditional Chinese Medicine(2023BSJJ02) （2023BSJJ02）
Application for the Research Project of National Clinical Research Base of Traditional Chinese Medicine(20-21ZY2115) （20-21ZY2115）
Henan University of Traditional Chinese Medicine Graduate Students'Research Innovation Project(2022KYCX057) 国家自然科学基金资助项目(82204981) （2022KYCX057）
国家中医临床研究基地科研专项(2021JDZX2002) （2021JDZX2002）
食管中医文献数据库公共信息平台研究(STG-ZYY06202146) （STG-ZYY06202146）
河南中医药大学博士科研基金项目(2022BSJJ08) （2022BSJJ08）
河南中医药大学博士科研基金项目(2023BSJJ02) （2023BSJJ02）
国家中医临床研究基地科研专项(20-21ZY2115) （20-21ZY2115）
河南中医药大学研究生"科研创新"类项目申请书(2022KYCX057) （2022KYCX057）
