血小板/淋巴细胞比值对重度创伤性颅脑损伤患者30d内病死风险的预测价值OA北大核心CSTPCD

Aim:To assess the relation between platelet-to-lymphocyte ratio(PLR)and 30-day death risk in patients with severe traumatic brain injury(STBI),as well as its predictive value for death risk.Methods:In this retrospective co-hort study,clinical data of 133 patients were collected in the Neurological Intensive Care Unit of the First Affiliated Hospital of Zhengzhou University who met the diagnostic criteria of STBI from January 1,2020 to January 1,2022.The differences in clinical indicators between the death group(n=45)and survival group(n=88)were compared.Three regression models[neutrophil-to-lymphocyte ratio(NLR),PLR,and NLR+PLR]were developed to assess the influencing factors of 30-day death risk.Modified Poisson regression analysis was employed to determine the predictive value of PLR for 30-day death risk among patients with STBI.Results:NLR and PLR demonstrated significant relation with the prognosis of patients suffering from STBI(P<0.05).NLR(OR=0.963,95%CI was 0.929-0.999,P=0.044)and PLR(OR=0.995,95%CI was 0.991-0.998,P=0.005)were associated with30-day death risk in STBI patients.Results from modified Poisson regres-sion analysis revealed that low PLR might increase 30-day death risk in STBI patients(RR=0.999,95%CI was 0.999-1.000,P=0.002).Conclusion:PLR serves as a risk factor for30-day death risk in patients with STBI,and demonstrates high predictive value.