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补阳还五汤干预急性心肌梗死疾病机制的研究进展OACSTPCD

Research progress of the mechanisms of Buyang Huanwu Decoction intervening in acute myocardial infarction

中文摘要英文摘要

急性心肌梗死(AMI)是一种急性发作的冠脉综合征,已成为严重影响人类生活健康的重大疾病,中医药对AMI具有较好的治疗效果,近年来补阳还五汤干预AMI的作用成为了研究的热点.现代药理学研究表示补阳还五汤具有抗血栓、保护血管、抗炎症和抑制细胞凋亡的作用,补阳还五汤具有多靶点,多通路全方位治疗的优点.从保护血管内皮、促进血管生成、抑制心肌重构、抑制炎症因子、抑制细胞凋亡等方面对补阳还五汤干预AMI的研究进展进行综述,为AMI的中医药诊疗研究提供文献依据.

Acute myocardial infarction(AMI)is an acute coronary syndrome,which has become a major disease that seriously affects human life and health.Traditional Chinese medicine can achieve a good therapeutic effect in the treatment of the disease.In recent years,its effect in this regard has become a research hotspot.Modern pharmacological studies have shown that Buyang Huanwu Decoction features the effects of anti-thrombosis,protecting blood vessels,anti-inflammation and inhibiting apoptosis,showcasing its advantages of multi-target and multi-pathway as a comprehensive therapy.This paper reviews the research progress of Buyang Huanwu Decoction in the intervention of AMI from the aspects of protecting vascular endothelium,promoting angiogenesis,inhibiting myocardial remodeling,inhibiting inflammatory factors and inhibiting apoptosis,so as to provide a literature basis for the diagnosis and treatment of AMI in traditional Chinese medicine.

路美娟;徐永康;徐强

天津中医药大学第二附属医院,天津 300150天津中医药大学,天津 301617

临床医学

补阳还五汤心肌梗死血管内皮血管生成机制

Buyang Huanwu Decoctionmyocardial infarctionvascular endotheliumangiogenesismechanism

《吉林中医药》 2024 (005)

604-608 / 5

赵英强天津市名中医传承工作室;2021年度天津市教委科研计划自然重点项目(2021ZD028)

10.13463/j.cnki.jlzyy.2024.05.025

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