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基于DNA步行器的传感器技术在食品安全检测中的研究进展

宋思青 司晓夏 胡聚峰 杜子沫 陈历俊 刘继超

食品工业科技2024,Vol.45Issue(12):395-404,10.
食品工业科技2024,Vol.45Issue(12):395-404,10.DOI:10.13386/j.issn1002-0306.2023080091

基于DNA步行器的传感器技术在食品安全检测中的研究进展

Research Progress of Sensors Technology Based on DNA Walker in Food Safety Detection

宋思青 1司晓夏 1胡聚峰 1杜子沫 1陈历俊 1刘继超1

作者信息

  • 1. 北京三元食品股份有限公司,国家母婴乳品健康工程技术研究中心,北京市乳品工程技术研究中心,母乳研究技术创新中心,北京 100163
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摘要

Abstract

With the rapid development of DNA nanotechnology,DNA molecules with various structures and functions are used to construct programmable nanomachines with dynamic behaviors.Thereinto,DNA walker possesses the advantages of the cascade signal amplification generated by the autonomous movement along the predetermined track by driving force,which is widely applied in the biosensing,biological imaging,and drug delivery fields,thus showing the great application potential for rapid and ultrasensitive detection of contaminants in food.This review first briefly introduces the basic principles of DNA walker,and describes the strategies for improving the efficiency of DNA walker in detail,then summarizes its applications in the food safety detection.Finally,the future research directions of DNA walkers are prospected to provide theoretical guidance for its real applications.

关键词

食品安全/DNA步行器/信号放大/核酸适配体/生物传感器

Key words

food safety/DNA walker/signal amplification/nucleic acid aptamers/biosensors

分类

轻工纺织

引用本文复制引用

宋思青,司晓夏,胡聚峰,杜子沫,陈历俊,刘继超..基于DNA步行器的传感器技术在食品安全检测中的研究进展[J].食品工业科技,2024,45(12):395-404,10.

基金项目

2021-国家乳创中心-11"原奶和乳制品微生物安全与品质控制技术研究". ()

食品工业科技

OA北大核心CSTPCD

1002-0306

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