食品科学2024，Vol.45Issue(11)：285-292,8.DOI:10.7506/spkx1002-6630-20231010-068
超高效合相色谱法快速测定食品复合包装袋中7种异氰酸酯类化合物的残留量及迁移量
Rapid Determination of Residues and Migration of Seven Isocyanate Compounds in Food Composite Packaging Bags by Ultra-high Performance Convergence Chromatography
摘要
Abstract
An ultra-high performance convergence chromatography(UPC2)method was developed to rapidly determine the residues and migration of seven isocyanate compounds in food composite packaging bags.The separation was performed on an ACQUITY UPC2 HSS C18 SB column using gradient elution with a mobile phase consisting of CO2 and methanol.The column temperature was 40 ℃,and the system back pressure was 13.10 MPa.The analytes were detected by a photo diode array(PDA)detector and quantified by an external standard method.The results showed that under the optimal conditions,baseline separation of the seven isocyanate compounds could be achieved within 2 min.The detection limits were in the range of 1.0-3.0 μg/kg,and the quantitation limits were in the ranged from 5.0 to 10.0 μg/kg.At spiked levels of 10,125 and 625 μg/kg,the recoveries of the isocyanate compounds ranged from 85.1％to 108.4％,and the relative standard deviations(RSDs)ranged from 0.7％to 6.5％.The developed method was used to determine 40 batches of food composite packaging bag samples.Isocyanate compounds residues were found in 7 batches,among which the contents of TDI and DPI residues were relatively high,but no isocyanates were found to migrate from these positive samples.The establishment of this method can provide technical support for the determination of the residues and migration of isocyanate compounds in food composite packaging bags.关键词
超高效合相色谱/食品复合包装袋/异氰酸酯类化合物/残留量/迁移量Key words
ultra-high performance convergence chromatography/food composite packaging bags/isocyanate compounds/residues/migration分类
化学引用本文复制引用
邱月,李根容,余秋玲,谭超兰,陆嘉莉,张清..超高效合相色谱法快速测定食品复合包装袋中7种异氰酸酯类化合物的残留量及迁移量[J].食品科学,2024,45(11):285-292,8.基金项目
重庆市科技局科研院所绩效激励引导专项(cstc2022jxjl50001) （cstc2022jxjl50001）
重庆市市场监督管理局科研计划项目(CQSJKJ2022040) （CQSJKJ2022040）
重庆市市场监督管理局科研计划项目(CQSJKJDW2023003) （CQSJKJDW2023003）
