肌少症病人超声参数与体质指数、骨密度及骨骼肌质量指数的关系OA北大核心CSTPCD

Objective:To explore the relationship between ultrasound parameters and body mass index(BMI),bone mineral density(BMD)and skeletal muscle mass index(SMMI)in patients with sarcopenia.Methods:60 patients with sarcopenia in Second Hospital of Shanxi Medical University were regarded as study group from January 1,2023 to January 1,2024,and 50 healthy volunteers with gender and age matching who came to our hospital for physical examination during the same period were selected as control group.Ultrasound examination was performed in both groups to record gastrocnemius muscle thickness(MT),maximum cross-sectional area(CA)and muscle hardness(Young' s modulus values during contraction and relaxation).Dual-energy X-ray absorption method was used to record BMD and limb muscle mass and calculate the SMMI and BMI.The differences in the above indicators were compared.Logistic regression analysis was used to screen the influencing factors of sarcopenia.ROC curve was applied to analyze the diagnostic efficiency of ultrasound parameters on sarcopenia.Pearson correlation coefficient was adopted to analyze the correlation between ultrasound parameters and BMI,BMD and SMMI in study group.Results:Logistic regression analysis showed that MT,CA,Young's modulus values during contraction and relaxation,BMI,BMD and SMMI were independent influencing factors of sarcopenia(P<0.05).ROC curve revealed that the AUCs of MT,CA,Young' s modulus values during contraction and relaxation in the diagnosis of sarcopenia were 0.908,0.958,0.909,0.932 respectively.Pearson correlation coefficient manifested that MT,CA and Young' s modulus values during contraction and relaxation were positively correlated with BMI,BMD and SMMI in patients with sarcopenia(P<0.05).Conclusion:Ultrasound parameters are helpful for screening and diagnosis of sarcopenia.Ultrasound parameters MT,CA and muscle hardness are significantly correlated with BMI,BMD and SMMI.