畜牧与兽医2024，Vol.56Issue(6)：49-54,6.
灌服肠内酯对哺乳羔羊瘤胃发酵参数和消化道发育的影响
Effect of enterolactone by gavage on rumen fermentation parameters and gastrointestine development in sucking lambs
摘要
Abstract
This study aimed to investigate the effects of enterolactone infusion on the rumen fermentation parameters and gastrointestine de-velopment in lambs.Fourteen healthy 12-day-old lambs were used and randomly divided into two groups:the control group received saline infusion,while the experimental group received enterolactone infusion.The lambs were orally administered daily at 10:00.Then,the lambs were fed with ad libitum with a mixture of 1∶9 goat milk powder and water,and their food intake was recorded daily and they weighed week-ly.At 42 days of age,the lambs were slaughtered and samples of rumen and small intestine tissues,as well as rumen fluid,were taken from them for histomorphological and volatile fatty acid analyses,respectively.The results of the experiment showed that:Oral administration of enterolactone significantly increased the average daily weight gain of lambs at five weeks of age(P＜0.019).Oral administration of enterolac-tone significantly reduced the proportion of acetate in the rumen of the lambs(P=0.019)as well as the acetic acid to propionic acid ratio in them(P=0.019).Compared with the control group,oral administration of enterolactone significantly increased the proportion of fully differ-entiated papillae in the rumen of lambs of the experimental group(P=0.013),increased the thickness of their rumen wall(P=0.004),length(P＜0.001),width(P＜0.001),density(P＜0.001),and surface area(P＜0.001)of their rumen papillae,and significantly in-creased the thickness of their stratum corneum(P=0.004),as well as the thickness of the spinous layer and basal layer in them(P＜0.001).Compared with the control group,oral administration of enterolactone significantly increased the height of the villi in the duodenum(P＜0.001)and jejunum of the experimental group,as well as the villus height to crypt depth ratio in the duodenum in them(P＜0.001),but significantly reduced the crypt depth in their duodenum(P＜0.001).In conclusion,oral administration of enterolactone altered the fer-mentation parameters of the rumen of the tested lambs,increased the thickness of their rumen wall,and significantly stimulated the prolifera-tion of their rumen epithelium,increased the height of their small intestinal villi and enhanced the absorption capacity of their small intestine.关键词
肠内酯/瘤胃发酵/消化道发育/羔羊Key words
enterolactone/rumen fermentation/gastrointestine development/lambs分类
农业科技引用本文复制引用
刘宁,莫佳琪,王翊菲,黄士翰,刘军花..灌服肠内酯对哺乳羔羊瘤胃发酵参数和消化道发育的影响[J].畜牧与兽医,2024,56(6):49-54,6.基金项目
国家自然科学基金面上项目(32172752) （32172752）
江苏省大学生创新创业训练项目(202310307073Z) （202310307073Z）
