射频联合外用药物在增生性瘢痕治疗中的应用OACSTPCD

Scars occur after human trauma repair and the treatment of hypertrophic scar is still a hot and difficult problem.Treatments for scarring include medications,photovoltaic,and surgical therapies.Common anti-scar drugs include silicone gel,plant extracts.However local topical anti-scar medication shows low penetration efficiency because of the limitation of skin barrier.Radiofrequency(RF)is an electrical current generated by electromagnetic radiation.RF produces a thermal effect that can stimulate the synthesis and remodeling of collagen,which can be an effective prevention and treatment of hypertrophic scar.It is also a physical penetration method,which acts on the skin to produce subcutaneous microchannels,thus improving the percutaneous absorption of the drug.In this paper,the common topical anti-scar drugs and their mechanisms,the development of radiofrequency technology and the application of radiofrequency combined drugs in scar treatment were analyzed and summarized,which will help to further expand the clinical treatment of hypertrophic scar and improve its therapeutic effect.