中国医科大学学报2024，Vol.53Issue(5)：458-463,6.DOI:10.12007/j.issn.0258-4646.2024.05.012
2022年沈阳市某三级甲等医院细菌耐药监测结果分析
Analysis of bacterial resistance monitoring results in a tertiary hospital in Shenyang in 2022
郭丽洁 1杨书桓 2李富顺 1陈静静 1王齐晖 1褚云卓1
作者信息
- 1. 中国医科大学附属第一医院检验科,沈阳 110001
- 2. 沈阳药科大学药学院,辽宁 本溪 117004
- 折叠
摘要
Abstract
Objective To analyze pathogen distribution and drug resistance in a tertiary hospital in Shenyang in 2022 and provide evi-dence-based guidance for this and other hospitals to formulate antibacterial drug application strategies.Methods In 2022,bacterial iso-lates collected from patients in a tertiary hospital in Shenyang were identified and subjected to drug sensitivity tests based on the require-ments of the national clinical laboratory operation procedures.The data were analyzed using Whonet 5.6 software.Results In total,4968 pathogenic strains were isolated from this hospital in 2022.The top five isolates were Escherichia coli,Klebsiella pneumoniae,Acineto-bacter baumannii,Enterococcus faecalis,and Pseudomonas aeruginosa.The resistance rates of Escherichia coliand Klebsiella pneumo-niaeto carbapenems were 1.9%and 17.7%,respectively.The resistance rates of Enterobacter cloacaeto imipenem and meropenem were 26.7%and 25.0%,respectively.The isolation rate of methicillin-resistant Staphylococcus aureus(MRSA)was 15.6%.The resistance rates of vancomycin-resistant Enterococcusand linezolid-resistant Enterococcus faecaliswere 7.1%and 11.6%,respectively.The resist-ance rates of tropical yeasts to fluconazole was>20%.Conclusion The distribution and drug resistance of pathogens in this hospital differed from those in other regions of China.The drug resistance of strains in this hospital should be closely monitored to understand the distribution and drug resistance of pathogens in a timely manner and to provide guidance for the diagnosis and treatment of infections.关键词
细菌耐药监测/药敏试验/碳青霉烯耐药革兰氏阴性杆菌Key words
drug resistance monitoring/drug sensitivity test/carbapenem-resistant Gram-negative bacilli分类
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郭丽洁,杨书桓,李富顺,陈静静,王齐晖,褚云卓..2022年沈阳市某三级甲等医院细菌耐药监测结果分析[J].中国医科大学学报,2024,53(5):458-463,6.
