从"水火失济"论治房颤OACSTPCD
Treatment of Atrial Fibrillation from the Perspective of"Fire-Water Disharmony"
本文从君火、相火、肾水的关系探讨水火既济的过程,认为水火既济,体内如环运动,而水亏火旺、水盛火衰、君火不明相火失位皆可使水火失济,影响心神而发为心房颤动(房颤).西医学认为自主神经功能紊乱是房颤的重要原因,交感神经绝对或相对兴奋,心房肌细胞自律性增强,房室传导加快,表现为快速性房颤;迷走神经兴奋亦会导致心房电重构,延缓房室传导,表现为慢心室率房颤.自主神经系统受中枢神经系统支配,二者之间相互作用亦可诱发房颤.针对水火阴阳的失衡结合西医学对房颤机制的研究,本文提出"滋阴潜阳以治火""益火之源以培元""益气镇惊以调神",旨在促进心肾相交、水火相济、阴阳交感和合,恢复自主神经张力平衡,减少房颤发生的频次和持续时间,终止房颤的发作,拓宽临床治疗房颤的思路.
From the relationship between sovereign fire,minister fire and kidney water,we discussed the harmonization process of water and fire,and we think that water and fire harmoniously move in the body like a circle.While water deficiency with effulgent fire,water exuberance with fire debilitation,sovereign fire not bright,and failure of ministerial fire to perform work all can make water and fire lose their coordination,affecting heart spirit and resulting in atrial fibrillation.Western medicine believes that autonomic nervous disorder is an important cause of atrial fibrillation.The absolute or relative excitation of sympathetic nerve,the enhancement of atrial myocyte automaticity,and the acceleration of atrioventricular conduction can be manifested as tachyatrial fibrillation.Vagal excitation can also cause atrial electrical remodeling and delay atrioventricular conduction,which is manifested as slow ventricular rate atrial fibrillation.The autonomic nervous system is innervated by the central nervous system,and the interaction between the two can also induce atrial fibrillation.In response to the imbalance between water,fire,yin,and yang,combined with modern medical research on the mechanism of atrial fibrillation,we propose the treatment methods of"nourishing yin and suppressing yang to treat fire","benefiting the source of fire to cultivate vitality",and"supplementing qi and calming shock to regulate mind".The purpose of this is to promote the intersection of heart and kidney,the combination of water and fire,and the harmony of yin and yang,restore the balance of autonomic nervous system,reduce the frequency and duration of atrial fibrillation or terminate the onset of atrial fibrillation,and broaden the thought for the clinical treatment of atrial fibrillation.
黄欣雨;马勇博;张磊;姜枫;于杰;朱坤鹏
山东中医药大学,山东 济南 250014山东中医药大学附属医院,山东 济南 250014
中医学
水火失济房颤交感神经迷走神经自主神经功能紊乱中医治疗
Fire-water disharmonyAtrial fibrillationSympathetic nerveVagus nerveDysfunction of autonomic nervous systemTreatment of traditional Chinese medicine
《中医药学报》 2024 (006)
5-10 / 6
国家自然科学基金面上项目(81974561);山东省自然科学基金(ZR2017BH091);中国博士后科学基金(2017M612342);山东省中医药科技青年项目(2021Q114)
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