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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi

Neural Regeneration Research2025，Vol.20Issue(3)：P.845-857,13.

Neural Regeneration Research2025，Vol.20Issue(3)：P.845-857,13.DOI:10.4103/1673-5374.392889

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

Lin-Yan Huang ¹Yi-De Zhang ¹Jie Chen ¹Hai-Di Fan ²Wan Wang ¹Bin Wang ³Ju-Yun Ma ⁴Peng-Peng Li ³Hai-Wei Pu ³Xin-Yian Guo ¹Jian-Gang Shen ⁵Su-Hua Qi⁶

作者信息

1. School of Medical Technology,Xuzhou Key Laboratory of Laboratory Diagnostics,Xuzhou Medical University,Xuzhou,Jiangsu Province,China
2. School of Pharmacy,Xuzhou Medical University,Xuzhou,Jiangsu Province,China Department of Laboratory Medicine,Branch Hospital of Huai’an First People’s Hospital,Huai’an,Jiangsu Province,China
3. Department of Laboratory Medicine,the Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu Province,China
4. School of Pharmacy,Xuzhou Medical University,Xuzhou,Jiangsu Province,China
5. School of Chinese Medicine,The University of Hong Kong,Hong Kong Special Administrative Region,China
6. School of Medical Technology,Xuzhou Key Laboratory of Laboratory Diagnostics,Xuzhou Medical University,Xuzhou,Jiangsu Province,China School of Pharmacy,Xuzhou Medical University,Xuzhou,Jiangsu Province,China
折叠

摘要

关键词

cell differentiation/cerebral ischemia/reperfusion injury/chlorination/hypochlorous acid/microglia/neural stem cell/neurogenesis/nuclear translocation/stroke/β-catenin

分类

医药卫生

引用本文复制引用

Lin-Yan Huang,Yi-De Zhang,Jie Chen,Hai-Di Fan,Wan Wang,Bin Wang,Ju-Yun Ma,Peng-Peng Li,Hai-Wei Pu,Xin-Yian Guo,Jian-Gang Shen,Su-Hua Qi..Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke[J].Neural Regeneration Research,2025,20(3):P.845-857,13.

基金项目

supported by the Natural Science Foundation of Jiangsu Province of China,No.BK20211348(to SHQ) （to SHQ）

Xuzhou Basic Research Program,No.KC21030(to LYH) （to LYH）

Leadership Program of Xuzhou Medical University,No.JBGS202203(to SHQ) （to SHQ）

Research Grant Council GRF of Hong Kong Special Administrative Region of China,No.17105220(to JGS)。（to JGS）

Neural Regeneration Research

ISSN：1673-5374

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