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Good efficacy and safety profile of abrocitinib in Chinese adult patients with atopic dermatitis:A case series studyOACSTPCDMEDLINE

中文摘要

To the Editor:Atopic dermatitis(AD)is a chronic,relapsing inflammatory dermatosis with impairment of skin barrier function and immune dysfunction that affects both children and adults.It is characterized by eczematous lesions,pruritus,sleep disturbance,and diminished quality of life.Management of mild AD relies on emollients,topical corticosteroids,topical calcineurin inhibitors,and phototherapy,while systemic corticosteroids,immunosuppressive agents,and biologics are used for severe refractory cases.^([1])Systemic corticosteroids and immunosuppressants have many undesirable side effects.Patients with moderate-to-severe AD who do not respond adequately to topical therapies have few effective treatment options.

Yuqing Hu;Yan Zhao;Houmin Li;Cheng Zhou;Cong Yu;Zhanglei Mu;Xue Chen;Yuxin Wang;Jianzhong Zhang;

Department of Dermatology,Peking University People’s Hospital,Beijing 100044,China

临床医学

dermatitisimpairmentpatients

《Chinese Medical Journal》 2024 (006)

P.740-742 / 3

supported by grants from the National Natural Science Foundation of China(No.82103711);the Peking University People’s Hospital Research and Development Foundation(No.RDY2021-18)

10.1097/CM9.0000000000002838

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