腹腔去分化孤立性纤维性肿瘤1例OACSTPCD

Solitary fibrous tumor(SFT)is a rare mesenchymal tumor.Although most SFT are benign,dedifferentiated SFT can occur in some rare cases,which are more malignant and have a worse clinical prognosis.This paper reports a case of dedifferentiated SFT in the abdominal cavity in a 50-year-old female patient,who was admitted to the Hainan General Hospital with paroxysmal palpitations and facial flushing for 6 months.Laboratory tests were all normal.Abdominal CT showed a large lobulated soft tissue mass in the left adrenal area,approximately 11.7 cm×10.7 cm in size,with significant heterogeneous enhancement on contrast-enhanced scan.The patient underwent surgical resection of the tumor in the urology department.Microscopically,the tumor consisted of two parts,a spindle cell area and a sarcomatous area.The spindle cell area was a typical SFT,and the sarcomatous area was a dedifferentiated SFT.Immunohistochemically testing showed that both areas expressed cluster of differentiation 34(CD34)and signal transducer and activator of transcription 6(STAT6).NAB2-STAT6 gene fusion was also detected,ultimately confirming the diagnosis of dedifferentiated SFT.