临床与病理杂志2024，Vol.44Issue(3)：468-473,6.DOI:10.11817/j.issn.2095-6959.2024.240075
腹腔去分化孤立性纤维性肿瘤1例
A case of dedifferentiated solitary fibrous tumor in the abdominal cavity
摘要
Abstract
Solitary fibrous tumor(SFT)is a rare mesenchymal tumor.Although most SFT are benign,dedifferentiated SFT can occur in some rare cases,which are more malignant and have a worse clinical prognosis.This paper reports a case of dedifferentiated SFT in the abdominal cavity in a 50-year-old female patient,who was admitted to the Hainan General Hospital with paroxysmal palpitations and facial flushing for 6 months.Laboratory tests were all normal.Abdominal CT showed a large lobulated soft tissue mass in the left adrenal area,approximately 11.7 cm×10.7 cm in size,with significant heterogeneous enhancement on contrast-enhanced scan.The patient underwent surgical resection of the tumor in the urology department.Microscopically,the tumor consisted of two parts,a spindle cell area and a sarcomatous area.The spindle cell area was a typical SFT,and the sarcomatous area was a dedifferentiated SFT.Immunohistochemically testing showed that both areas expressed cluster of differentiation 34(CD34)and signal transducer and activator of transcription 6(STAT6).NAB2-STAT6 gene fusion was also detected,ultimately confirming the diagnosis of dedifferentiated SFT.关键词
孤立性纤维性肿瘤/去分化/临床病理特征Key words
solitary fibrous tumor/dedifferentiation/clinicopathologic features引用本文复制引用
魏清晨,王波..腹腔去分化孤立性纤维性肿瘤1例[J].临床与病理杂志,2024,44(3):468-473,6.基金项目
海南省重大科技计划项目(ZDKJ2021040).This work was supported by Major Science and Technology Program of Hainan Province,China(ZDKJ2021040). （ZDKJ2021040）
