针刺研究2024，Vol.49Issue(6)：625-633,9.DOI:10.13702/j.1000-0607.20230142
针刺参与缺血性脑卒中二级预防的研究进展
Progress of researches on mechanisms of acupuncture for secondary prevention of ischemic stroke
摘要
Abstract
Ischemic stroke(IS)is one of the main causes inducing death and disability in adults.Because of the high recurrence rate of IS,prevention of recurrence is of great significance to this population,for which the evidence-based and effective secondary prevention strategy is an important means,and acupuncture intervention has a positive effect on its risk factors.In the present article,we reviewed the progress of researches on the mechanisms of acupuncture underlying prevention of IS relapse from the perspective of its main risk factors,namely 1)hypertension(preventing and controlling the adverse effects caused by the imbalance of blood pressure level,vascular and other tissue structures,endocrine factors and central nervous system activities in patients with hypertension after IS),2)hypercholesterolemia(lowering serum total cholesterol,triglyceride,low-density lipoprotein-cholesterol(LDL-C)and raising high-density lipoprotein cholesterol),3)diabetes(regulating the secretion function of adipose tissue,activating the insulin signal transduction pathway,protecting the function of pancreatic β cells,and regulating the central nervous system functions to participate in the secondary prevention of IS),4)smoking(relieving the symptoms of smoking cessation and reducing the smoker's dependence on smoking by changing the internal environment,lowering the level of blood endorphin and regulating the excitability of central nervous system),5)sleep apnea syndrome(regulating local muscle function and the excitability of the nervous system,but also affecting some organic changes as reducing tonsil swelling)and 6)obesity(lowering blood glucose and lipid,increasing the ratio of brown/white fat,reducing leptin resistance,and suppressing appetite to induce body weight loss,or directly regulate the changes of fat tissue,etc).Results shows that the acupuncture's regulatory mechanism for IS risk factors is closely related to the neuroendocrine system,and simultaneously involves multiple targets of multiple risk factors.Due to its good efficacy and safety,acupuncture therapy is of great value for clinical promotion as an important intervention for secondary prevention.关键词
针刺/缺血性脑卒中/二级预防/危险因素Key words
Acupuncture/Ischemic stroke/Secondary prevention/Risk factors引用本文复制引用
周菁,付渊博,宋玉强,王璟霏,谢媛,王一战,杜鑫,赵冰骢..针刺参与缺血性脑卒中二级预防的研究进展[J].针刺研究,2024,49(6):625-633,9.基金项目
北京市科学技术委员会-首都临床特色诊疗技术研究及转化应用项目(No.Z221100007422078) （No.Z221100007422078）
2021年度"扬帆"计划重点医学专业(重点扶持专业)中西医结合康复项目(No.ZYLX202140) （重点扶持专业）
