全球鹿慢性消耗性疾病的发现与流行现状OA

Deer chronic wasting disease(CWD),as a prion disease affecting both domestic and wild deer animals,was firstly reported in the United States in 1980.For decades,the disease has spread uncontrollably in Northern America,leading to outbreaks in 30 states in the United States and 5 provinces in Canada.Cases has also been found recently in Europe.By the end of 2023,the disease was found in 6 countries including the United States,Canada,Norway,Finland,Sweden and Republic of Korea,but mainly in Northern America including the United States and Canada,as well as in Northern Europe inlcuding Norway and Finland.The cases found in Republic of Korea,rather than those in other countries,were related to those in Northern America.Overall,the disease was increasingly spreading in the world,but with slow pace.A large number of cases infected with CWD were found,causing potential risks of environmental contamination by prions and potential infection to other companion animals and human.The inventory of wild and domestic deers exceeded one million in China where the disease had not been detected,though.In order to protect animals from any infection,strict import quarantine and other measures should be taken to prevent any introduction of the disease.In the paper,global outbreak and prevalence of the disease were described in details,expecting to enlighten the prevention of the disease in China.